Mozifor 20mg Injection contains Plerixafor, which is used to mobilize hematopoietic stem cells (HSCs) in the bloodstream for collection and transplantation. 

Brand Name: Mozifor

Composition: Plerixafor

Mechanism of Action:

Plerixafor is a CXCR4 antagonist that functions by preventing stromal cell-derived factor-1α (SDF-1α) from attaching to the hematopoietic stem cells' CXCR4 receptor. This promotes the release of HSCs into the bloodstream by interfering with their ability to remain in the bone marrow. Following mobilization, the stem cells can be harvested for transplantation.

Uses:

Stem Cell Transplantation

Dosage and Administration:

The recommended dose is 0.24 mg/kg body weight, administered subcutaneously.

Side Effects:

• Injection site reactions (pain, swelling, redness)
• Diarrhea
• Difficulty Breathing
• Swelling
• Rash
• Nausea
• Vomiting
• Fatigue
• Dizziness
• Headache

Safety Advise:

  Liver  

Information regarding the use of Mojifor 20mg Injection in liver disease patients is minimal. Kindly speak with your healthcare provider.

  Kidney  

Information regarding the use of Mojifor 20mg Injection in kidney disease patients is minimal. Kindly speak with your healthcare provider.

  Pregnancy  

Rituximab should only be used during pregnancy if clearly needed, as it can harm the fetus. Kindly speak with your healthcare provider.

  Breastfeeding  

Nursing mothers should not get a 20mg injection of Mojifor unless truly necessary. Kindly speak with your healthcare provider.

  Alcohol  

When using Mojifor 20mg Injection with alcohol, caution is suggested. Kindly speak with your healthcare provider.

Storage:

Store in a refrigerator between 2°C to 8°C. Do not freeze or shake the vial.

How to use this medication?

Plerixafor injection is a liquid that a physician or nurse administers subcutaneously, or beneath the skin, in a medical facility. For up to four consecutive days, it is typically administered once daily, eleven hours before to the blood cell extraction. You will start receiving a G-CSF medicine once daily for four days before to starting plerixafor injection treatment, and you will continue to get the G-CSF medication during your plerixafor injection treatment.

Disclaimer:

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Marketer details

Name: Hetero Drugs Ltd

Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA

Country of origin: India