Rpo 10000 IU Injection contains Human recombinant Erythropoetin Alfa, a synthetic version of a natural hormone called erythropoietin. It primarily serves to treat anemia, which is a low red blood cell count, brought on by chemotherapy, chronic renal disease, and other illnesses.

Brand Name: Rpo

Composition: Human recombinant Erythropoetin Alfa

Mechanism of Action:

By attaching to erythropoietin receptors on erythroid progenitor cells in the bone marrow, human recombinant erythropoietin Alfa (Epoetin Alfa) increases the generation of red blood cells. This binding stimulates the proliferation and development of these progenitor cells by activating intracellular signaling pathways, including the JAK2/STAT5 pathway. Consequently, Epoetin Alfa improves hemoglobin levels and red blood cell synthesis, which improves the blood's ability to carry oxygen and reduces anemic symptoms.

Uses:

• Anemia in Chronic Kidney Disease 
• Anemia Due to Chemotherapy
• Anemia in HIV-Infected Patients

Dosage and Administration:

Depending on the patient's health, Rpo is injected intravenously (into a vein) or subcutaneously (under the skin). The patient's hemoglobin levels, the underlying reason of their anemia, and how well they respond to treatment all affect the dosage.

Side Effects:

• Headache
• Nausea
• Fever
• Vomiting
• Joint Pain
• Chills
• Cough
• High Blood Pressure
• Dizziness
• Weight Loss
• Insomnia

Safety Advise:

Liver  

Patients with liver illness should use Rpo 10000 Injection with caution. Rpo 10000 Injection dosage adjustments might be required. Kindly speak with your healthcare provider.

Kidney  

Patients with renal illness should use Rpo 10000 Injection with caution. Rpo 10000 Injection dosage adjustments might be required. Kindly speak with your healthcare provider.

  Pregnancy  

Animal studies suggest that Rpo 10000 injection could be harmful to the fetus, so it may not be safe to use during pregnancy. Before using it, discuss benefits and risks with your healthcare provider.

Breast Feeding  

Using Rpo 10000 Injection while nursing is most likely dangerous. The medication may damage the developing baby if it enters the breastmilk, according to limited human data. Kindly speak with your healthcare provider.

Alcohol  

It is unknown if drinking alcohol while using Rpo 10000 Injection is unsafe. Kindly speak with your healthcare provider.

Driving  

You may get adverse reactions from Rpo 10000 Injection that might affect your driving. Kindly speak with your healthcare provider.

Storage:

Store in the refrigerator at 2°C to 8°C. Do not freeze it. Protect it from light and keep it out of reach of children.

References:

1. Corwin HL, Gettinger A, Fabian TC, May A, Pearl RG, Heard S, An R, Bowers PJ, Burton P, Klausner MA, Corwin MJ. Efficacy and safety of epoetin alfa in critically ill patients. New England Journal of Medicine. 2007 Sep 6;357(10):965-76.

2. Das G. Epoetin alfa and beta differ in their erythropoietin isoform compositions and biological properties. British journal of haematology. 1998 Jan 1;100(1).

3. Markham A, Bryson HM. Epoetin alfa: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in nonrenal applications. Drugs. 1995 Feb;49:232-54.

4. Dammacco F, Castoldi G, Rödjer S. Efficacy of epoetin alfa in the treatment of anaemia of multiple myeloma. British Journal of Haematology. 2001 Apr;113(1):172-9.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: RPG Life Sciences Ltd

Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Country of origin: India