Chemodoc 120mg Injection contains Docetaxel, a chemotherapy medication used to treat various cancers, including breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, and head and neck cancer.
Inform your doctor if you have heart, liver, or kidney issues, or if you're taking medications for infections, as interactions may occur. This medicine isn't recommended during pregnancy or breastfeeding; effective contraception is advised during treatment.
Chemodoc 120mg Injection contains Docetaxel, a chemotherapy medication used to treat various cancers, including breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, and head and neck cancer.
Brand Name: Chemodoc
Composition: Docetaxel
Mechanism of Action:
By encouraging the formation of microtubules from tubulin dimers and preventing their disintegration, docetaxel functions. By stabilizing the microtubules and restricting their normal activity during mitosis, or cell division, this stops cancer cells from growing and spreading and ultimately results in cell death.
Uses:
Dosage and Administration:
The type of cancer being treated and the course of treatment affect the dosage of docetaxel, which is typically determined by the patient's body surface area (BSA). given as an infusion using an intravenous (IV).
Side Effects:
Safety Advise:
Liver
Patients with hepatic impairment may require dose modifications. Throughout treatment, liver function should be routinely assessed. Kindly speak with your healthcare provider.
Kidney
Patients with renal impairment may require dose modifications. Throughout treatment, kidney function should be routinely assessed. Kindly speak with your healthcare provider.
Pregnancy
As docetaxel may harm the fetus, it is not advised to use it during pregnancy. Kindly speak with your healthcare provider.
Breast Feeding
Chemodoc 120mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. Kindly speak with your healthcare provider.
Alcohol
Drinking alcohol while taking Chemodoc 120mg Injection is not advised. Kindly speak with your healthcare provider.
Storage:
Store the vial at 2°C to 8°C (36°F to 46°F) in a refrigerator. Do not freeze. Protect from light.
How to use this Medication?
This medication is administered intravenously. A medical expert with specialized training administers it in a hospital or clinic.
Consult your pediatrician about this medication's use in kids. Extra caution could be required.
References:
1. Cortes JE, Pazdur R. Docetaxel. Journal of Clinical Oncology. 1995 Oct;13(10):2643-55.
2. Baker J, Ajani J, Scotté F, Winther D, Martin M, Aapro MS, von Minckwitz G. Docetaxel-related side effects and their management. European journal of oncology nursing. 2009 Feb 1;13(1):49-59.
3. Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005 Dec;65:2513-31.
4. Pienta KJ. Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer. InSeminars in oncology 2001 Aug 1 (Vol. 28, pp. 3-7). WB Saunders.
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