I Nem 500 mg Injection contains Imipenem and Cilastatin as its active ingredients. It is a combination antibiotic used to treat severe bacterial infections.

Brand Name: I Nem

Composition: Imipenem and Cilastatin

Mechanism of Action:

Imipenem inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. Whereas Cilastatin Blocks the enzyme dehydropeptidase in the kidneys, which normally deactivates imipenem. This ensures that imipenem reaches the systemic circulation intact and can perform its antibacterial action.

Uses:

• Lower Respiratory Tract Infections: Pneumonia, bronchitis.
• Intra-abdominal Infections: Peritonitis, abdominal abscesses.
• Urinary Tract Infections (UTIs): Complicated UTIs caused by resistant bacteria.
• Gynecological Infections: Endometritis, pelvic inflammatory disease.
• Skin and Soft Tissue Infections: Cellulitis, wound infections.
• Bone and Joint Infections: Osteomyelitis, septic arthritis.
• Septicemia: Blood infections caused by bacteria.

Side Effects:

• Nausea
• Vomiting
• Fever
• Dizziness
• Diarrhea
• Localized pain at the injection site
• Rash
• Swelling
• Seizures

Safety Advise:

Kidney  

Dose adjustment may be needed for patients with kidney impairment. Kindly speak with your healthcare provider.

Liver  

Dose adjustment may be needed for patients with liver problems. Kindly speak with your healthcare provider.

Pregnancy  

Using I Nem 500mg Injection while pregnant may be dangerous. Kindly speak with your healthcare provider.

Breast Feeding  

INEM 500mg injection may pass into breast milk. Kindly speak with your healthcare provider.

Alcohol  

Avoid drinking alcohol as it may make you more drowsy and dizzy. Kindly speak with your healthcare provider.

Storage:

Store in a cool, dry place below 25°C. Use immediately or store in a refrigerator, and use within 24 hours if diluted.

Disclaimer:

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