U-Tryp 100000IU Injection contains the protease inhibitor Ulinastatin, which has immunomodulatory and anti-inflammatory effects. Its main application is in the treatment of ailments marked by high levels of inflammation.

Brand Name: U-Tryp

Composition: Ulinastatin

Mechanism of Action:

Ulinastatin functions by blocking a number of proteolytic enzymes that contribute to tissue injury and inflammation, including trypsin and elastase. Suppressing these enzymes lowers the activation of inflammatory pathways and alters the immune system, which may lessen tissue damage and reduce inflammation.

Uses:

·       Acute pancreatitis

·       Severe sepsis

·       Acute respiratory distress syndrome

·       Post-surgical inflammation and trauma

Dosage and Administration:

One to two vials (100,000 IU each) are usually injected intravenously over the course of an hour, one to three times a day for three to five days. The patient's age and the intensity of their symptoms may influence the dosage.

Side Effects:

·       Nausea

·       Vomiting

·       Diarrhea

·       Skin rash

·       Itching

·       Headache

·       Injection site reactions (pain, swelling)

·       Difficulty breathing

·       Swelling of the face or throat, hives

·       Fever

·       Persistent sore throat

·       Abnormal bleeding or bruising

Safety Advise:

Lungs  

The safety of U-tryp Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of U-tryp Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of U-tryp Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

U-tryp should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using U-tryp while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Store in a refrigerator between 2°C and 8°C. Avoid freezing. Stay away from light, heat, and moisture.

References:

1.     Atal SS, Atal S. Ulinastatin–a newer potential therapeutic option for multiple organ dysfunction syndrome. Journal of Basic and Clinical Physiology and Pharmacology. 2016 Mar 1;27(2):91-9.

2.     Karnad DR, Bhadade R, Verma PK, Moulick ND, Daga MK, Chafekar ND, Iyer S. Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study. Intensive care medicine. 2014 Jun;40:830-8.

3.     Fang S, Li P, Zhu C, Han X, Bao P, Guo W. Research progress of ulinastatin in the treatment of liver diseases. International Journal of Clinical and Experimental Pathology. 2020 Nov 1;13(11):2720.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Bharat Serums & Vaccines Ltd

Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Country of origin: India