Adcetris 50mg Injection contains Brentuximab Vedotin, an antibody-drug conjugate used in the treatment of certain types of cancers, including Hodgkin lymphoma and systemic anaplastic large cell lymphoma (sALCL). 

Brand Name: Adcetris

Composition: Brentuximab vedotin

Mechanism of Action:

An antibody-drug combination (ADC) called Brentuximab Vedotin is made up of a cytotoxic substance called monomethyl auristatin E (MMAE) and a monoclonal antibody called Brentuximab. It targets the protein CD30, which is present on cancerous cells in diseases such as anaplastic large cell lymphoma and Hodgkin lymphoma. The medication is internalized after binding to CD30, releasing MMAE to interfere with microtubule activity, resulting in cell cycle arrest and triggering apoptosis.

Uses:

·       Hodgkin lymphoma

·       Systemic anaplastic large cell lymphoma

Dosage and Administration:

Usually, Adcetris is given as an intravenous infusion. Under the guidance of a medical professional skilled in intravenous medicine administration, the infusion should be administered over a period of thirty minutes.

Side Effects:

·       Numbness

·       Tingling

·       Pain in hands or feet

·       Fever

·       Chills

·       Nausea

·       Cough

·       Shortness of breath

·       Infections (due to a reduced white blood cell count)

·       Neutropenia

·       Thrombocytopenia

·       Anemia

Safety Advise:

Lungs  

The safety of Adcetris Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Adcetris Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Adcetris Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Adcetris should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Adcetris while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Keep the vial in the original carton to protect from light.

How to use this Medication?

In a hospital or doctor's office, a doctor or nurse will mix a powdered form of benuximab vedotin with fluid and administer it intravenously (into a vein) during a 30-minute period. Depending on the condition for which you are receiving therapy, benuximab vedotin is typically injected once every two to three weeks for as long as your doctor advises.

If you have certain side effects, your doctor might need to stop your therapy, change your dosage, or postpone it. Throughout your brentuximab vedotin injectable treatment, be sure to let your doctor know how you're feeling.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Takeda Pharmaceuticals India Pvt. Ltd

Address: The Capital A 1504, 16 Floor, G Block, Bandra Kurla Complex-Bandra East, Mumbai - 400051

Country of origin: India