Armotraz 1mg Tablet contains Anastrozole, a medication used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is a member of the class of medications known as aromatase inhibitors, which function by reducing the body's production of estrogen.

Brand Name: Armotraz

Composition: Anastrozole

Mechanism of Action:

The enzyme aromatase, which the body uses to change androgens into estrogens, is inhibited by anastrozole. It aids in slowing or halting the growth of estrogen-dependent breast cancer cells by lowering estrogen levels.

Uses:

Breast Cancer

Dosage and Administration:

Take 1 mg tablet once daily. Can be taken with or without food. It is generally prescribed for long-term use, depending on the patient's response and treatment plan.

Side Effects:

• Hot flashes
• Joint pain
• Weakness
• Fatigue
• Nausea
• Bone thinning
• Headache
• Rash
• Swelling

Safety Advise:

Liver  

Regular monitoring of liver function is advised, as anastrozole may cause changes in liver enzymes. Kindly speak with your healthcare provider.

Kidney  

Regular monitoring of kidney function is advised, as anastrozole may cause changes in kidney impairment. Kindly speak with your healthcare provider.

Pregnancy  

There is clear evidence that using Armotraz tablets during pregnancy poses a harm to the growing fetus. Kindly speak with your healthcare provider.

Breast Feeding  

Using Armotraz tablets during nursing is not advised. Evidence points to the drug's potential to be hazardous to the unborn child. Kindly speak with your healthcare provider.

Alcohol  

The safety of drinking alcohol while taking Armotraz tablets is unknown. Kindly speak with your healthcare provider.

Storage:

Store at a room temperature of 25°C (77°F). Keep the tablets in a dry place, away from excessive moisture.

How to use this Medication?

Anastrozole is taken orally as a tablet at the same time every day, usually once daily, with or without food. Pay close attention to your doctor's instructions and don't change the dosage unless specifically instructed.

Anastrozole may be required for a number of years or more. Keep taking anastrozole even if you feel better. Consult your doctor before ceasing to take anastrozole.

References:

1.   Sreejith KR, Rajagopal PL, Premaletha K. Analytical Method Development and Validation of Anostrozole in Pure and Tablet Dosage Form by UV Spectroscopy. Research Journal of Pharmacy and Technology. 2017;10(4):1015-9.

2.      Kelly CM, Buzdar AU. Anastrozole. Expert opinion on drug safety. 2010 Nov 1;9(6):995-1003.

3.      Lønning PE, Geisler J, Dowsett M. Pharmacological and clinical profile of anastrozole. Breast cancer research and treatment. 1998 May;49:S53-7.

4.     Cuzick J, Sestak I, Forbes JF, Dowsett M, Knox J, Cawthorn S, Saunders C, Roche N, Mansel RE, von Minckwitz G, Bonanni B. Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial. The Lancet. 2014 Mar 22;383(9922):1041-8.

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Marketer details

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Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India