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Akynzeo 300mg/0.5mg Capsule

Category: Others

Manufacturer: Glenmark Pharmaceuticals Ltd

Combination: Netupitant, Palonosetron

Akynzeo 300mg/0.5mg Capsule is a fixed-dose combination medication containing Netupitant (300mg) and Palonosetron (0.5mg). It is used to prevent nausea and vomiting brought on by chemotherapy for cancer, including chemotherapy that is both severely and mildly emetogenic.

If you are pregnant or nursing, let your doctor know. Patients with liver and kidney disorders should not take this medication. If you have a medical condition or are on medication, let your doctor know. Because this medication may cause drowsiness or vertigo, it is strongly discouraged that you drive or operate heavy machinery while undergoing therapy.

 

Akynzeo 300mg/0.5mg Capsule is a fixed-dose combination medication containing Netupitant (300mg) and Palonosetron (0.5mg). It is used to prevent nausea and vomiting brought on by chemotherapy for cancer, including chemotherapy that is both severely and mildly emetogenic.


Brand Name: Akynzeo


Composition: Netupitant (300mg), Palonosetron (0.5mg)


Mechanism of Action:

Netupitant and Palonosetron work together to prevent chemotherapy-induced nausea and vomiting (CINV) by targeting different phases of the condition. Netupitant lessens the effects of substance P, a major contributor to the delayed phase of CINV, by blocking NK1 receptors in the central nervous system. In the meanwhile, palonosetron successfully stops the acute phase of CINV by blocking 5-HT3 receptors in the brain and gastrointestinal system. Comprehensive protection against chemotherapy-related nausea and vomiting is offered by this dual mechanism.


Uses:

Nausea and Vomiting due to chemotherapy


Dosage and Administration:

Take one capsule orally about an hour prior to treatment.


Side Effects:

  • Fatigue
  • Constipation
  • Dyspepsia
  • Headache

Safety Advise: 

Liver  

Liver function should be monitored regularly, as Akynzeo can cause abnormalities in liver. Kindly speak with your healthcare provider.

 

Kidney  

Kidney function should be monitored regularly, as Akynzeo can cause abnormalities in kidney. Kindly speak with your healthcare provider.

 

Pregnancy  

Akynzeo should not be used while pregnant due to the potential harm it can cause to the fetus. Kindly speak with your healthcare provider.

 

Breastfeeding  

When using this drug, it is not advised. If you are or will be breastfeeding, Kindly speak with your healthcare provider.

 

Driving  

Akynzeo may make you tired or dizzy. Till you understand how the medicine affects you. Kindly speak with your healthcare provider.


Storage:

Store Akynzeo at room temperature, away from moisture and heat.


Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.


Marketer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: Ireland

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