Celrixafor Injection contains Plerixafor, a hematopoietic stem cell mobilizer. Enhancing the release of bone marrow stem cells into the bloodstream for collection and transplantation is a typical use for it.
Since interactions can happen, let your doctor know if you have renal problems, abnormal blood cell levels, or are taking any other medications. Avoid using it when pregnant or nursing, and make sure to utilize good contraception while undergoing treatment to avoid getting pregnant.
Celrixafor Injection contains Plerixafor, a hematopoietic stem cell mobilizer. Enhancing the release of bone marrow stem cells into the bloodstream for collection and transplantation is a typical use for it.
Brand Name: Celrixafor
Composition: Plerixafor
Mechanism of Action:
Plerixafor is an antagonist of the CXCR4 chemokine receptor. It interferes with the retention of hematopoietic stem cells in the bone marrow and encourages their mobilization into the peripheral circulation for collection by blocking the interaction between CXCR4 and its ligand (SDF-1α).
Uses:
Autologous Stem Cell Transplantation
Dosage and Administration:
Given as an injection under the skin. usually administered 11 hours prior to apheresis at a dose of 0.24 mg/kg.
Side Effects:
Safety Advise:
Kidney 
Patients with severe renal disease should exercise caution while using Celrixafor Injection. Kindly speak with your healthcare provider.
Liver
Celrixafor Injection should be administered with caution to individuals suffering from liver disease. Kindly speak with your healthcare provider.
Pregnancy
Celrixafor Injection is not recommended for usage during pregnancy since there is clear evidence of danger to the developing infant. Kindly speak with your healthcare provider.
Breast Feeding
Celrixafor Injection is not safe to use when breast feeding. Kindly speak with your healthcare provider.
Alcohol
Celrixafor Injection of alcohol may produce extreme sleepiness. Kindly speak with your healthcare provider.
Storage:
Store in a refrigerator (2°C to 8°C). Do not freeze. Protect from light.
How to use this Medication?
Plerixafor injection is a liquid that a physician or nurse administers subcutaneously, or beneath the skin, in a medical facility. For up to four consecutive days, it is typically administered once daily, eleven hours before to the blood cell extraction. You will start receiving a G-CSF medicine once daily for four days before to starting plerixafor injection treatment, and you will continue to get the G-CSF medication during your plerixafor injection treatment.
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Marketer details
Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Country of origin: India
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