Gonapress 0.25mg Injection contains Cetrorelix, a gonadotropin-releasing hormone (GnRH) antagonist. Its primary application in fertility treatments is to prevent premature ovulation during assisted reproductive procedures such as in vitro fertilization (IVF). By suppressing the luteinizing hormone (LH), eggs are released at the ideal period for fertilization.
Inform your doctor if you have liver or renal illness, are nursing, or are taking any other medications that may interfere with the medication's effectiveness.
Gonapress 0.25mg Injection contains Cetrorelix, a gonadotropin-releasing hormone (GnRH) antagonist. Its primary application in fertility treatments is to prevent premature ovulation during assisted reproductive procedures such as in vitro fertilization (IVF).
Brand Name: Gonapress
Composition: Cetrorelix
Mechanism of Action:
Cetrorelix is a GnRH antagonist. It competes with GnRH receptors in the pituitary gland, inhibiting endogenous GnRH. This inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). As a result, it prevents early ovulation during regulated ovarian stimulation.
Uses:
· Female infertility treatment
· Prostate cancer
Dosage and Administration:
Subcutaneous (under the skin) injection is usually given in the upper leg or belly. Should be administered by a healthcare practitioner or under their supervision.
Side Effects:
· Injection site reactions such as Redness, itching, swelling, or irritation.
· Nausea
· Vomiting
· Headache
· Abdominal pain
· Swelling of the face, lips, tongue, or throat
· Severe dizziness
· Fainting
Safety Advise:
Lungs
The safety of Gonapress Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Gonapress Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Gonapress Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Gonapress should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Using Gonapress while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Storage:
Keep refrigerated at 2°C to 8°C; do not freeze.
How to use this medication?
This medication is to be injected under the skin. It may be administered by a healthcare practitioner in a hospital or clinic environment. If you receive this medicine at home, you will be trained how to prepare and administer it. Use precisely as directed. Take your medications at regular times. Do not take your medication more frequently than prescribed.
It is critical that you store your used needles and syringes in a designated sharps receptacle. Do not place them in a trash can. If you don't have a sharps container, contact your pharmacist or healthcare practitioner to obtain one.
References:
1. Lizio R, Klenner T, Borchard G, Romeis P, Sarlikiotis AW, Reissmann T, Lehr CM. Systemic delivery of the GnRH antagonist cetrorelix by intratracheal instillation in anesthetized rats. European journal of pharmaceutical sciences. 2000 Jan 1;9(3):253-8.
2. Leroy I, d’Acremont MF, Brailly-Tabard S, Frydman R, de Mouzon J, Bouchard P. A single injection of a gonadotropin-releasing hormone (GnRH) antagonist (Cetrorelix) postpones the luteinizing hormone (LH) surge: further evidence for the role of GnRH during the LH surge. Fertility and sterility. 1994 Sep 1;62(3):461-7.
3. Telegdy G, Tanaka M, Schally AV. Effects of the LHRH antagonist Cetrorelix on the brain function in mice. Neuropeptides. 2009 Jun 1;43(3):229-34.
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