Inflitza 25mg Capsule contains Midostaurin, a multi-targeted kinase inhibitor used in the treatment of specific types of cancers, particularly acute myeloid leukemia (AML) and advanced systemic mastocytosis (ASM). Midostaurin functions by inhibiting several kinases that are essential for the development and spread of cancer cells.

Brand Name: Inflitza

Composition: Midostaurin

Mechanism of Action:

Some malignancies have overactive receptor tyrosine kinases, such as FLT3 (FMS-like tyrosine kinase, KIT, and others, which are inhibited by the targeted medication midostaurin. It primarily targets FLT3 mutations, which are responsible for the leukemia cells' fast growth and proliferation in acute myeloid leukemia (AML). It inhibits KIT signaling in systemic mastocytosis, which lowers aberrant mast cell growth and relieves related symptoms. Because of its dual activity, midostaurin effectively treats various disorders by directly disrupting the molecular pathways that drive the course of the disease.

Uses:

• Acute Myeloid Leukemia
• Advanced Systemic Mastocytosis

Dosage and Administration:

50 mg twice a day, or every 12 hours, when receiving chemotherapy. In order to increase absorption and lessen gastrointestinal adverse effects, capsules should be taken with food.

Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Fatigue
• Headache
• Fever
• Muscle and joint pain
• Rash

Safety Advise:

Lungs  

The safety of Inflitza Capsule for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Inflitza Capsule for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Inflitza Capsule for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

   Pregnancy

Inflitza should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Inflitza while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Keep at room temperature (20–25°C), out of direct sunlight and dampness. Avoid freezing.

How to use this Medication?

Drink a glass of water along with this medication. Observe the medicine label's instructions. Take this medication with food. Avoid taking grapefruit juice with it. This medication should not be sliced, crushed, or chewed. Take your medication on a regular basis. Avoid taking it more frequently than prescribed. Except as directed by your physician, do not discontinue taking.

Consult your pediatrician about this medication's use in kids. Extra caution could be required.

Disclaimer:

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