Tenvir AF 25mg Tablet contains Tenofovir Alafenamide (TAF), which is a prodrug of Tenofovir and is used basically for the treatment of chronic hepatitis B and HIV infection.
Inform your doctor if you have skin problems or liver/kidney disease, and you may need regular blood tests while using this medicine. Avoid alcohol, consult your doctor if pregnant or breastfeeding, and practice safe sex to prevent HIV transmission if you are HIV positive.
Tenvir AF 25 mg Tablet contains Tenofovir Alafenamide (TAF), which is a prodrug of Tenofovir and is used basically for the treatment of chronic hepatitis B and HIV infection.
Brand Name: Tenvir AF
Composition: Tenofovir Alafenamide
Mechanism of Action:
The body transforms tenofovir alafenamide into tenofovir, which subsequently suppresses the reverse transcriptase enzyme. By preventing viral replication, this activity lowers the viral burden and promotes immune system recovery.
Uses:
Chronic Hepatitis B virus infection
HIV Infection
Dosage and Administration:
For chronic hepatitis B, a dosage of 25 mg once daily is typically suggested. The dosage for HIV treatment may change according on the particular combination regimen that is advised.
Side Effects:
Safety Advise:
Bone 
Long-term use may raise concerns regarding the loss of bone mineral density. It is recommended to keep an eye on bone health, particularly in those who have osteoporosis or other fracture risk factors. Kindly speak with your healthcare provider.
Liver
It may be essential to perform routine liver function testing, particularly for individuals with liver disease. Kindly speak with your healthcare provider.
Kidney
It may be essential to perform routine renal function testing, particularly for individuals with renal disease. Kindly speak with your healthcare provider.
Pregnancy
It is important to speak with your healthcare provider before using Tenvir AF 25mg Tablet if you are pregnant or intend to become pregnant.
Breast Feeding
The possible dangers to the newborn are not fully known, considering the fact that Tenvir AF 25mg Tablet is excreted into human breast milk. Kindly speak with your healthcare provider.
Alcohol
It is usually advised to stay away from drinking too much alcohol when using Tenvir AF 25mg Tablet. Kindly speak with your healthcare provider.
Storage:
Store the tablet at room temperature, between 15°C to 30°C (59°F to 86°F). Humidity: Keep the medication in a dry place and protect it from moisture.
How to use this Medication?
Take this medication orally at the same time every day, as directed on the prescription label, along with a glass of water and food. Unless your care team advises you otherwise, take your medication as prescribed; skipping doses increases the risk of developing viral resistance.
Discuss the usage of this drug in children with your care team. Precautions do need to be taken, even though it can be administered to kids as young as 12 for specific conditions.
Get in touch with an emergency department or poison control center right away if you believe you may have taken too much of this medication.
References:
1. De Clercq E. Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF). Biochemical pharmacology. 2016 Nov 1;119:1-7.
2. Wassner C, Bradley N, Lee Y. A review and clinical understanding of tenofovir: tenofovir disoproxil fumarate versus tenofovir alafenamide. Journal of the International Association of Providers of AIDS Care (JIAPAC). 2020 Apr 15;19:2325958220919231.
3. Scott LJ, Chan HL. Tenofovir alafenamide: a review in chronic hepatitis B. Drugs. 2017 Jun;77(9):1017-28.
4. Gibson AK, Shah BM, Nambiar PH, Schafer JJ. Tenofovir alafenamide: a review of its use in the treatment of HIV-1 infection. Annals of Pharmacotherapy. 2016 Nov;50(11):942-52.
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