Bryxta 400mg Injection contains Bevacizumab, a monoclonal antibody used in cancer therapy. It functions by preventing angiogenesis, which is how cancers create their own blood supply.

Brand Name: Bryxta

Composition: Bevacizumab

Mechanism of Action:

It seeks out and attaches itself to vascular endothelial growth factor (VEGF), a protein that stimulates blood vessel development. Bevacizumab stops VEGF from attaching to its receptors on endothelial cells, which stops new blood vessels from forming and stops tumor development and metastasis.

Uses:

• Metastatic Colorectal Cancer
• Non-Small Cell Lung Cancer
• Breast Cancer
• Glioblastoma
• Ovarian Cancer
• Cervical Cancer

Dosage and Administration:

Depending on the particular malignancy being treated and the patient's general health, the dosage may change. A gradual intravenous infusion of bevacizumab is administered; the infusion rate can be changed according to the patient's tolerance.

Side Effects:

• Hypertension
• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Fever
• Dizziness
• Increased risk of bleeding

Safety Advise:

Liver  

Caution is advised in patients with hepatic impairment, and dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Kidney  

Caution is advised in patients with renal impairment, and dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Pregnancy  

It should only be used if absolutely necessary because its safety during pregnancy has not been thoroughly demonstrated. Kindly speak with your healthcare provider.

Breast Feeding  

Using Bryxta Injection while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Alcohol  

Alcohol consumption while using Bryxta Injection is not advised. Kindly speak with your healthcare provider.

Storage:

Bryxta Injection should be kept out of direct sunlight and at room temperature, between 20°C and 25°C.

How to use this Medication?

Usually given once every two or three weeks, bevacizumab injection is a liquid that a medical expert administers slowly into a vein. The dosage schedule is customized based on your individual condition and response to treatment.

When the drug is infused, bevacizumab injectable products have the potential to induce severe side effects. Notify your doctor right once if you suffer from any of the following symptoms: headaches, dizziness, chest discomfort, flushing, itching, rash, hives, chills, shaking, sweating, or shortness of breath. If you have these or other side effects, your doctor might need to reduce the rate of your infusion or postpone or terminate your treatment.

References:

1.     Kazazi-Hyseni F, Beijnen JH, Schellens JH. Bevacizumab. The oncologist. 2010 Aug;15(8):819.

2.      Braghiroli MI, Sabbaga J, Hoff PM. Bevacizumab: overview of the literature. Expert review of anticancer therapy. 2012 May 1;12(5):567-80.

3.      Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology. 2007 May 1;114(5):855-9.

4.      Keating GM. Bevacizumab: a review of its use in advanced cancer. Drugs. 2014 Oct;74(16):1891-925.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Zydus Cadila

Address: Zydus Corporate Park, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, Sarkhej - Gandhinagar Highway, Ahmedabad, Gujarat, India - 382481. 

Country of origin: India