Imatib 400mg Tablet contains Imatinib mesylate is used to treat a number of malignancies, such as dermatofibrosarcoma protuberans, acute lymphocytic leukemia, gastrointestinal stromal tumors, and chronic myeloid leukemia. 

Brand Name: Imatib

Composition: Imatinib mesylate

Mechanism of Action:

The Philadelphia chromosome produces the BCR-ABL fusion protein, which is the target of the selective tyrosine kinase inhibitor (TKI) imatinib. Imatinib inhibits this protein, which stops the signaling pathways that encourage cancer cells to proliferate and expand, ultimately causing apoptosis (cell death) in those cells.

Uses:

• Chronic Myeloid Leukemia (CML)
• Acute Lymphoblastic Leukemia (ALL)
• Gastrointestinal Stromal Tumors (GISTs)
• Dermatofibrosarcoma Protuberans (DFSP)

Side effects:

·         Nausea

·         Vomiting

·         Diarrhea

·         Fatigue

·         Muscle cramps

·         Rash

·         Anemia

·         Heart failure

·         Edema

·         Pleural effusion

Dosage and administration:

To minimize gastrointestinal discomfort, take orally with water and meals if possible. For CML, a beginning dosage of 400 mg once daily is typical. The dose for GISTs may be raised to 800 mg based on response and tolerance. Clinical discretion may be used to modify doses.

Safety advices:

Kidney  

Patients with renal illness should take imatinib 400 tablets with care. It could be necessary to alter the Imatib 400 Tablet's dosage. Kindly speak with your healthcare provider. 

Liver  

Patients who suffer from severe liver disease should use imatinib 400 tablets with care. It could be necessary to alter the Imatib 400 Tablet's dosage. Kindly speak with your healthcare provider.

Pregnancy  

It is not safe to take Imatib 400 Tablet during pregnancy due to clear evidence of danger to the developing fetus. Kindly speak with your healthcare provider. 

Breast feeding  

It is most likely not safe to take Imatib 400 Tablet during nursing. The medication may damage the unborn child if it enters the breastmilk. Kindly speak with your healthcare provider.

Alcohol  

It is unknown if drinking alcohol while taking an Imatib 400 Tablet is safe. Kindly speak with your healthcare provider. 

Driving  

The negative effects of Imatib 400 Tablet may impair your driving skills. Kindly speak with your healthcare provider.

Storage:

Keep the product at room temperature; the recommended range is 20°C to 25°. Store away from moisture and in a dry environment. Keep out of direct sunlight and keep in original packaging. Keep out of children grasp.

How to use this Medication?

To reduce stomach discomfort, take the medication orally along with a full glass of water and food; do not take the medication with grapefruit juice. Take the medication as directed by your doctor, as often as prescribed, and don't stop taking it without first talking to them. Seek assistance if you are having difficulty swallowing, and call emergency services if you think you may have overdosed.

Disclaimer:

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