Lonopin 40mg Injection contains Enoxaparin, a low molecular weight heparin (LMWH) used as an anticoagulant to prevent and treat blood clots. It is frequently administered to patients who require anticoagulant medication or who have a risk of deep vein thrombosis (DVT) or pulmonary embolism (PE).

Brand Name: Lonopin

Composition: Enoxaparin

Mechanism of Action:

Inhibiting clotting factor Xa (anti-factor Xa activity) and, to a lesser extent, clotting factor IIa (thrombin) is how enoxaparin sodium acts. This results in an anticoagulant action that aids in preventing blood clot formation.

Uses:

·         Deep Vein Thrombosis

·         Pulmonary Embolism

·         Acute Coronary Syndromes

·         Heparin-Induced Thrombocytopenia

·         Prophylaxis in Dialysis

Dosage and Administration:

Dosage varies according to the frequency. dosage modified in accordance with the patient's status. Administration Route is Intravenous or subcutaneous (in some situations, including ACS).

Side Effects:

·         Injection site reactions

·         Bleeding

·         Anemia

·         Nausea

·         Vomiting

·         Headache

·         Fever

·         Diarrhea

·         Thrombocytopenia

·         Allergic reactions (rash, itching, swelling)

·         Spinal hematoma

Safety Advise:

Liver  

If you have liver disease, let your doctor know. Lonopin 40mg Injection should be used with caution if you have liver illness.

Kidney  

Patients with kidney issues may require dosage changes because of increased medication development. Kindly speak with your healthcare professional.

Pregnancy  

Generally considered safe in pregnancy but should be used under medical supervision. Kindly speak with your healthcare professional.

Breast Feeding  

Generally considered safe during nursing but should be used under medical supervision. Kindly speak with your healthcare professional.

Alcohol  

It is unknown if drinking alcohol while taking lonopin is safe. Kindly speak with your healthcare professional.

Storage:

Store at room temperature (below 25°C). Do not freeze. Keep in the original packaging to protect from light.

How to use this Medication:

Subcutaneous injections of enoxaparin are usually administered twice a day for a period of 10 to 14 days. Use the medication exactly as prescribed by your doctor, and observe any cautions.

Use enoxaparin as prescribed even if you feel good. Enoxaparin should not be stopped without consulting your doctor.

You will be instructed by your healthcare professional on how to inject enoxaparin into various abdomen sites. Each syringe should only be used once, and it should be disposed away properly.

References:

1.     Iqbal Z, Cohen M. Enoxaparin: a pharmacologic and clinical review. Expert opinion on pharmacotherapy. 2011 May 1;12(7):1157-70.

2.     Tripathi KD. Essentials of medical pharmacology. Jaypee Brothers medical publishers; 2018 Oct 31.

3.     Casele HL, Laifer SA, Woelkers DA, Venkataramanan R. Changes in the pharmacokinetics of the low-molecular-weight heparin enoxaparin sodium during pregnancy. American journal of obstetrics and gynecology. 1999 Nov 1;181(5):1113-7.

4.     Ingle RG, Agarwal AS. A world of low molecular weight heparins (LMWHs) enoxaparin as a promising moiety—A review. Carbohydrate polymers. 2014 Jun 15;106:148-53.

Disclaimer:

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Marketer details

Name: Bharat Serums & Vaccines Ltd

Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Country of origin: India