Mikastar 500mg Injection contains Amikacin is a member of the aminoglycoside class of antibiotics. Serious bacterial infections, particularly those brought on by Gram-negative bacteria, are its main use.
Excessive dosages of this medication may result in hearing loss, renal damage, or balance problems. Avoid use when pregnant or nursing; regular monitoring and adherence to your doctor's instructions are crucial.
Mikastar 500mg Injection contains Amikacin is a member of the aminoglycoside class of antibiotics. Serious bacterial infections, particularly those brought on by Gram-negative bacteria, are its main use.
Brand Name: Mikastar
Composition: Amikacin
Mechanism of Action:
The active component of Mikastar 500mg Injection, amikacin, works by preventing the formation of bacterial proteins. It attaches itself to the bacterial 30S ribosomal subunit, preventing the synthesis of vital proteins and ultimately causing bacterial cell death. It works well against a wide variety of germs because of its bactericidal action.
Uses:
Bacterial Infection
Dosage and Administration:
This Injection is administered by doctors or nurses either intravenously or intramuscularly. Age, weight, renal function, and the severity of the infection all affect dosage.
Side Effects:
· Injection site reactions (pain, swelling, redness)
· Nausea or vomiting
· Diarrhoea
· Skin rashes
· Hearing loss
· Balance issues
Safety Advise:
Lungs
The safety of Mikastar Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Mikastar Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Mikastar Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Mikastar should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Using Mikastar while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Storage:
Keep the temperature at less than 25°C. Avoid freezing. Keep out of children's reach.
How to use this Medication?
Every eight or twelve hours (two or three times a day), amikacin injection is administered as a liquid intravenously (into a vein) or intramuscularly (into a muscle). Amikacin is typically infused (given gradually) over 30 to 60 minutes when administered intravenously. The sort of infection you have determines how long your therapy will last.
Amikacin can be injected into your body in a hospital or administered at home. Your healthcare practitioner will demonstrate how to utilize amikacin injection if you will be receiving it at home. Make sure you comprehend these instructions, and if you have any concerns, consult your healthcare practitioner.
References:
1. Ramirez MS, Tolmasky ME. Amikacin: uses, resistance, and prospects for inhibition. Molecules. 2017 Dec 19;22(12):2267.
2. Kawaguchi H. Discovery, chemistry, and activity of amikacin. Journal of Infectious Diseases. 1976 Nov 1;134(Supplement_2): S242-8.
3. Black RE, Lau WK, Weinstein RJ, Young LS, Hewitt WL. Ototoxicity of amikacin. Antimicrobial agents and chemotherapy. 1976 Jun;9(6):956-61.
4. Bodey GP, Valdivieso M, Feld R, Rodriguez V. Pharmacology of amikacin in humans. Antimicrobial agents and chemotherapy. 1974 May;5(5):508-12.
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Marketer details
Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Country of origin: India
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