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Cabolong 40mg Tablet contains Cabozantinib as its active ingredient. By blocking many receptor tyrosine kinases (RTKs) involved in tumor growth, metastasis, and angiogenesis, the tyrosine kinase inhibitor (TKI) cabotinib is used to treat a variety of cancer types.
Inform your doctor if you have heart, liver, kidney issues, or high blood pressure before taking Cabolong 40mg Tablet. Avoid use during pregnancy or breastfeeding, and use effective contraception during treatment.
Cabolong 40mg Tablet contains Cabozantinib as its active ingredient. By blocking many receptor tyrosine kinases (RTKs) involved in tumor growth, metastasis, and angiogenesis, the tyrosine kinase inhibitor (TKI) cabotinib is used to treat a variety of cancer types.
Brand Name: Cabolong
Composition: Cabozantinib
Mechanism of Action:
Multiple tyrosine kinases, such as MET, VEGFR, and RET, which are implicated in several pathways essential for tumor cell development and angiogenesis (blood vessel creation), are inhibited by cabotinib. Cabozantinib can decrease the blood supply to tumors and impede the growth and spread of cancer cells by blocking these kinases.
Uses:
Dosage and Administration:
Depending on the type of cancer being treated and patient characteristics like liver or renal function, the usual dosage for Cabolong is 40–60 mg once daily. It must be taken at least two hours before or after a meal, on an empty stomach.
Side Effects:
Safety Advise:
Liver
For patients with liver issues, dose modifications might be necessary, and routine liver function monitoring is advised. Kindly speak with your healthcare provider.
Kidney
For patients with kidney issues, dose modifications might be necessary, and routine renal function monitoring is advised. Kindly speak with your healthcare provider.
Pregnancy
Cabozantinib is not advised during pregnancy since it may harm the fetus. Kindly speak with your healthcare provider.
Breast Feeding
Cabolong 40mg Tablet is probably unsafe to use during breastfeeding. Kindly speak with your healthcare provider.
Alcohol
The safety of combining alcohol with Cabolong 40mg Tablet is unknown. Kindly speak with your healthcare provider.
Storage:
Store at room temperature between 15°C and 30°C (59°F and 86°F). Keep in a dry place, protected from direct light and moisture.
How to use this Medication?
Cabozantinib is a pill that is typically given once a day, either one hour before or two hours after meals, on an empty stomach. Pay close attention to what your doctor tells you, and don't change the dosage without consulting your doctor.
Drink a full glass of water and swallow the tablets whole. Avoid opening, crushing, chewing, and splitting them.
References:
1. Lacy SA, Miles DR, Nguyen LT. Clinical pharmacokinetics and pharmacodynamics of cabozantinib. Clinical pharmacokinetics. 2017 May;56:477-91.
2. Abou-Alfa GK, Meyer T, Cheng AL, El-Khoueiry AB, Rimassa L, Ryoo BY, Cicin I, Merle P, Chen Y, Park JW, Blanc JF. Cabozantinib in patients with advanced and progressing hepatocellular carcinoma. New England Journal of Medicine. 2018 Jul 5;379(1):54-63.
3. Maroto P, Porta C, Capdevila J, Apolo AB, Viteri S, Rodriguez-Antona C, Martin L, Castellano D. Cabozantinib for the treatment of solid tumors: a systematic review. Therapeutic advances in medical oncology. 2022 Jun;14:17588359221107112.
4. Fallahi P, M Ferrari S, Di Bari F, Materazzi G, Benvenga S, Miccoli P, Antonelli A. Cabozantinib in thyroid cancer. Recent Patents on Anti-Cancer Drug Discovery. 2015 Sep 1;10(3):259-69.
Disclaimer:
The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.
Marketer details
Name: MSN Laboratories
Address: MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA
Country of origin: India
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