Posid 50mg Capsule contains Etoposide, a chemotherapeutic agent primarily used in the treatment of various cancers. It works very well against lung cancer, testicular cancer, and some types of leukemia.

Brand Name: Posid

Composition: Etoposide

Mechanism of Action:

Inhibiting topoisomerase II, an enzyme necessary for DNA replication, is how etoposide functions. It stops DNA strands from re-ligating after they have been cut, which causes DNA breaks and eventually causes cancer cells to undergo apoptosis (programmed cell death) by stabilizing the topoisomerase II-DNA complex.

Uses:

• Testicular Cancer
• Small Cell Lung Cancer
• Acute Lymphoblastic Leukemia

Dosage and Administration:

Administration using intravenous (IV) routes. The precise ailment being treated, the patient's general health, and other variables all affect dosage.

Side Effects:

·       Nausea

·       Vomiting

·       Diarrhea

·       Rash

·       Headache

·       Weakness

·       Fever

·       Anemia

·       Neutropenia

·       Difficulty breathing

·       Allergic reactions

·       Mouth sores

·       Constipation

Safety Advise:

Kidney  

Dose adjustments are required in patients with renal impairment. Kindly speak with your healthcare provider.

Liver  

Liver function tests should be monitored during prolonged treatment, especially in patients with liver disease, as etoposide can cause elevated liver enzymes. Kindly speak with your healthcare provider.

Pregnancy  

Use etoposide during pregnancy only if clearly needed and under medical supervision, as its safety during pregnancy is not fully established.  Kindly speak with your healthcare provider.

Breast Feeding  

Caution is advised during breastfeeding since the drug can pass into breast milk. Kindly speak with your healthcare provider.

Alcohol  

The safety of using Posid 50mg capsulewith alcohol is unknown. Kindly speak with your healthcare provider.

Storage:

Store at room temperature (below 25°C) in a dry place, protected from light. Keep out of reach of children.

References:

1.      Slevin ML. The clinical pharmacology of etoposide. Cancer. 1991 Jan 1;67(S1):319-29.

2.      Montecucco A, Zanetta F, Biamonti G. Molecular mechanisms of etoposide. EXCLI journal. 2015;14:95.

3.      Baldwin EL, Osheroff N. Etoposide, topoisomerase II and cancer. Current Medicinal Chemistry-Anti-Cancer Agents. 2005 Jul 1;5(4):363-72.

4.      Van Maanen JM, Retel J, De Vries J, Pinedo HM. Mechanism of action of antitumor drug etoposide: a review. JNCI: Journal of the National Cancer Institute. 1988 Dec 7;80(19):1526-33.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Cadila Pharmaceuticals Ltd

Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.

Country of origin: India