Fasenra 30mg Injection contains Benralizumab, a monoclonal antibody used for treating severe eosinophilic asthma by reducing eosinophil levels in the blood.

Brand Name: Fasenra

Composition: Benralizumab

Mechanism of Action:

A monoclonal antibody called benralizumab targets the alpha subunit of the interleukin-5 receptor (IL-5Rα), which is present on basophils and eosinophils. It suppresses IL-5 signaling, which is essential for eosinophil development and survival, by attaching itself to IL-5Rα. Furthermore, it causes antibody-dependent cell-mediated cytotoxicity (ADCC), which causes eosinophils to rapidly diminish. By successfully lowering eosinophilic inflammation, a primary cause of asthma flare-ups, this mechanism lessens the frequency of severe asthma episodes and improves symptoms.

Uses:

Severe eosinophilic asthma

Dosage and Administration:

For the first three doses of the first phase, 30 mg is administered subcutaneously once every four weeks. After that, 30 mg is administered subcutaneously once every eight weeks during the maintenance phase.

Side Effects:

• Headache
• Sore throat
• Cough
• Injection site reactions (pain, erythema, swelling)

Safety Advise:

Lungs  

The safety of Fasenra Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Fasenra Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Fasenra Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Fasenra should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

   Breast Feeding  

Using Fasenra while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Fasenra should be kept in the refrigerator between 2°C and 8°C (36°F and 46°F). The formulation may be harmed by freezing, so avoid doing so.

How to use this Medication?

This drug is administered subcutaneously. You'll learn how to prepare and administer it. Follow the instructions on the medicine label. Unless instructed otherwise by your care team, continue taking it.

Make careful to remove the outer needle cover from the pen before administering the dosage. It's crucial to store used syringes and needles in a designated sharps container. Keep them out of the garbage can. Get a sharps container by calling your care team or pharmacist if you don't already have one.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: AstraZeneca

Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Country of origin: India