Repatha SureClick Injection contains Evolocumab, a PCSK9 inhibitor used to lower cholesterol levels in patients with high LDL cholesterol, particularly in cases of familial hypercholesterolemia or atherosclerotic cardiovascular disease. 

Brand Name: Repatha Sureclick

Composition: Evolocumab

Mechanism of Action:

PCSK9, a protein that attaches to liver cell LDL receptors, is inhibited by evolocumab. Repatha dramatically reduces LDL levels by blocking PCSK9, which expands the pool of LDL receptors accessible to remove LDL cholesterol from the blood.

Uses:

• Hyperlipidemia (High cholesterol)
• Homozygous Familial Hypercholesterolemia

Dosage and Administration:

Subcutaneous injection is the method of administration. 140 mg every two weeks or 420 mg once a month is the recommended dosage for primary hyperlipidemia.

Side Effects:

• Injection site reactions (redness, pain, swelling)
• Rash
• Difficulty Breathing
• Back Pain
• Nasopharyngitis

Safety Advise: 

Lungs  

The safety of Repatha Sureclick Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Repatha Sureclick Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Repatha Sureclick Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Repatha Sureclick should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Repatha Sureclick while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Store in a refrigerator at 2°C to 8°C. Keep out of the light. Avoid freezing.

How to use this Medication?

For subcutaneous use, evolocumab can be purchased as a prefilled syringe, autoinjector, or on-body infusor. It can be given every two weeks or every month as directed for HeFH, cardiovascular disease, or HoFH. Pay close attention to what your doctor says, and don't change the dosage or regimen without consulting a doctor.

Evolocumab injections (420 mg dose) should be administered once every month using an on-body infusor and prefilled cartridge, or three separate injections spaced out over 30 minutes, each administered with a different prefilled syringe or prefilled autoinjector.

Disclaimer:

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