Esentra 120mg injection contains Denosumab, used to treat osteoporosis and avoid bone problems in cancer patients. By blocking the RANK ligand protein, it lowers the risk of fracture and bone loss. For patients with moderate renal impairment, monitoring renal function is recommended.

Brand Name: Esentra

Composition: Denosumab

Mechanism of Action:

Denosumab acts by blocking RANKL, a protein involved in the erosion (breakdown) of bone. Denosumab enhances bone mass and decreases bone loss by inhibiting RANKL.

Uses:

• Osteoporosis
• Bone metastases
• Multiple myeloma
• Bone loss caused by hormone treatment for prostate or breast cancer

Dosage and Administration:

Given via subcutaneous injection, usually every 6 months for osteoporosis (Prolia) or more frequently (every 4 weeks) for cancer-related indications (Xgeva).

Side Effects:

• Joint pain
• Back pain
• Skin reactions at the injection site 
• Fatigue
• Hypocalcemia
• Increased risk of infections, particularly skin infections (e.g., cellulitis)
• Osteonecrosis of the jaw
• Fractures of the thigh bone 

Safety Advise:

 Kidney  

 Hypocalcemia is more common in patients with moderate to severe renal dysfunction. It's critical to regularly monitor kidney function. Do contact your Healthcare professional.

Liver  

 Those with severe liver disease should use Esentra 120 Injection with caution. Esentra 120 Injection dosage adjustments can be required. Kindly speak with your healthcare provider.

Allergy  

 If you have allergic response symptoms like swelling, redness, or trouble breathing, get medical help immediately.

Bone  

 An unusual fracture of the femur can occasionally result from Denosumab. Inform your physician of any new or unexpected hip, groin, or thigh pain.

Pregnancy  

 Not recommended during pregnancy. Discuss risks with your doctor if you are planning to conceive.

Breast Feeding    

 Using Esentra 120 Injection while nursing is most likely dangerous. The medication may damage the unborn child if it enters the breastmilk, according to limited human data.

Storage:

Esentra 120mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Do not freeze it.

How should I use this Medication?

This medication is injected subcutaneously. It is delivered at a hospital or clinic by a medical professional. 

You will receive a personalized MedGuide prior to every treatment. Every time, make sure to carefully read this information.

Consult your pediatrician about Prolia and the usage of this medication in young patients. There might be a need for extra caution. Consult your physician about the usage of Xgeva in young patients. Precautions do apply even though this medication may be administered for specific diseases to youngsters as young as 13 years old.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.