Carbotero 450mg Injection contains Carboplatin, which is a platinum-based chemotherapy drug used to treat various types of cancer. Carboplatin inhibits the growth and division of cancer cells by interfering with their DNA.

Brand Name: Carbotero

Composition: Carboplatin

Mechanism of Action:

Carboplatin is a member of the alkylating agent class. It creates cross-links with cancer cells' DNA, preventing RNA production and DNA replication and ultimately causing the cancer cells to die. Because carboplatin has less adverse effects than its predecessor, cisplatin, especially when it comes to kidney toxicity, it is frequently chosen.

Uses:

• Ovarin Cancer
• Head and Neck Cancer
• Lung Cancer

Dosage and Administration:

The patient's body surface area, renal function, and the particular cancer type being treated are taken into consideration while determining the Carbotero dosage. Under the guidance of an oncologist, it is often given as an intravenous (IV) infusion in a clinical environment.

Side Effects:

• Nausea
• Vomiting
• Anemia
• Diarrhea
• Low blood platelets
• Myelosuppression
• Fatigue
• Electrolyte imbalances (such as low magnesium, sodium, or potassium)
• Hair loss

Safety Advise:

Liver  

Regular monitoring is necessary because carboplatin can impact liver function. Kindly speak with your healthcare provider.

Kidney  

Regular monitoring is necessary because carboplatin can impact liver function. Kindly speak with your healthcare provider.

Pregnancy  

Since it may harm the fetus, carboplatin is not advised during pregnancy. Kindly speak with your healthcare provider.

Breast Feeding  

Using carbotero 450mg injection while nursing is not advised. Evidence points to the drug's potential to be hazardous to the unborn child. Kindly speak with your healthcare provider.

Alcohol  

The safety of drinking alcohol while using carbotero 450mg injection is unknown. Kindly speak with your healthcare provider.

Storage:

Store at a controlled room temperature, typically between 15°C and 25°C (59°F and 77°F). Protect from light.

How to use this Medication?

In a medical facility, a doctor or nurse will inject a solution (liquid) called carboplatin intravenously (into a vein) over a minimum of 15 minutes. Typically, it is administered once every four weeks.

References:

1.      van der Vijgh WJ. Clinical pharmacokinetics of carboplatin. Clinical pharmacokinetics. 1991 Oct;21(4):242-61.

2.      Go RS, Adjei AA. Review of the comparative pharmacology and clinical activity of cisplatin and carboplatin. Journal of Clinical Oncology. 1999 Jan;17(1):409-.

3.    Oguri S, Sakakibara T, Mase H, Shimizu T, Ishikawa K, Kimura K, Smyth RD. Clinical pharmacokinetics of carboplatin. The Journal of Clinical Pharmacology. 1988 Mar;28(3):208-15.

4.   Wagstaff AJ, Ward A, Benfield P, Heel RC. Carboplatin: a preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of cancer. Drugs. 1989 Feb;37:162-90.

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Marketer details

Name: Hetero Drugs Ltd

Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA

Country of origin: India