Mabura 40 mg Injection contains Adalimumab, is a biological medicine used in the treatment of various autoimmune conditions.

Brand Name: Mabura

Composition: Adalimumab

Mechanism of Action:

Adalimumab is a fully human monoclonal antibody that specifically binds to tumor necrosis factor-alpha (TNF-alpha), a substance in the body that plays a role in inflammation. Adalimumab lowers inflammation and modifies the immune response linked to autoimmune disorders by blocking TNF-alpha.

Uses:

• Rheumatoid Arthritis
• Juvenile Idiopathic Arthritis
•  Psoriatic Arthritis
• Ankylosing Spondylitis
• Crohn's Disease
• Ulcerative Colitis
• Plaque Psoriasis

Dosage and Administration:

The particular condition being treated determines the dosage. The first dose for many illnesses is usually 40 mg, given subcutaneously.

Side Effects:

• Injection site reactions (redness, swelling, itching)
• Headache
• Nausea
• Fatigue
• Rash
• Upper respiratory infections

Safety Advise:

Liver  

Keep an eye on your liver's enzyme levels because Adalimumab can have an impact on it. Kindly speak with your healthcare provider.

Kidney  

Information about the use of Mabura 40mg Injection in renal disease patients is limited. Kindly speak with your healthcare provider.

Pregnancy  

Unless directed by your physician, avoid using Mabura 40mg Injection while you are pregnant. Notify your doctor if you are expecting a child, are already pregnant, or want to get pregnant while receiving therapy. 

Breast Feeding  

Mabura 40 mg It is possible to utilize injections while nursing. But let your healthcare provider know if you're nursing a baby.

Alcohol  

Alcohol use along with Mabura 40mg Injection may result in negative side effects. Kindly speak with your healthcare provider.

Storage:

Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Protect from light and do not freeze.

How to use this Medication?

Adalimumab injection products are available as solutions in vials, pens, and prefilled syringes for subcutaneous administration; your doctor will decide the appropriate dosage based on your age and condition. Make sure you carefully read the label on your prescription, schedule your injection days on a calendar, and take the drug exactly as prescribed—that is, without changing the dosage.

Adalimumab injection products won't heal your disease; they will only help control it. Even if you feel better, keep using injection products containing adalimumab. Adalimumab injectable products should not be stopped without first consulting your doctor.

References:

1.  Sinha S, Ghosh B, Bandyopadhyay S, Fatima F, Bandi VK, Thakur P, Reddy B, Chary S, Talluri L, Gupta A, Kale AR. Comparative evaluation of efficacy, pharmacodynamics, and safety of Hetero’s adalimumab (Mabura®, Hetero Biopharma Ltd.) and reference adalimumab (Humira®, Abbvie Inc.) in patients with active rheumatoid arthritis on concomitant methotrexate therapy. BMC rheumatology. 2020 Dec;4:1-1.

2.      Scheinfeld N. Adalimumab: a review of side effects. Expert opinion on drug safety. 2005 Jul 1;4(4):637-41.

3.      Mease PJ. Adalimumab in the treatment of arthritis. Therapeutics and clinical risk management. 2007 Mar 30;3(1):133-48.

4.      Bang LM, Keating GM. Adalimumab: a review of its use in rheumatoid arthritis. BioDrugs. 2004 Mar;18(2):121-39.

5.     Sandborn WJ, Hanauer SB, Rutgeerts P, Fedorak RN, Lukas M, MacIntosh DG, Panaccione R, Wolf D, Kent JD, Bittle B, Li J. Adalimumab for maintenance treatment of Crohn’s disease: results of the CLASSIC II trial. Gut. 2007 Sep 1;56(9):1232-9.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Hetero Drugs Ltd

Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA

Country of origin: India