Glioz 250mg Capsule is an oral chemotherapy medication that contains Temozolomide, an alkylating agent used primarily in the treatment of specific types of brain cancer. Temozolomide interferes with the growth of cancer cells, helping to slow or stop their spread in the body.

Brand Name: Glioz

Compositon: Temozolomide

Mechanism of Action:

Temozolomide is an alkylating agent that works by adding alkyl groups to the DNA of cancer cells, which interferes with their replication. This leads to DNA damage, resulting in cell cycle arrest and apoptosis (cell death). It is especially effective against rapidly dividing cancer cells.

Uses:

·         Glioblastoma Multiforme

·         Anaplastic Astrocytoma

Dosage and Administration:

The dose is based on body surface area and the specific type of cancer being treated. Taken orally with a full glass of water, on an empty stomach or at bedtime to reduce nausea. Capsules should not be opened or crushed.

Side Effects:

·         Nausea

·         Vomiting

·         Fatigue

·         Headache

·         Constipation

·         Loss of appetite.

·         Anemia

·         Neutropenia

·         Thrombocytopenia

·         Severe infections

·         Stevens-Johnson syndrome

Safety Advise:

Liver  

Monitor liver function tests as Temozolomide can cause liver toxicity. Kindly speak with your healthcare provider.

Pregnancy  

Temozolomide is teratogenic and is contraindicated in pregnancy. Kindly speak with your healthcare provider.

Breast Feeding  

Using Glioz 250mg Capsules during nursing is not advised. Evidence points to the drug's potential to be hazardous to the unborn child. Kindly speak with your healthcare provider.

Alcohol  

The safety of drinking alcohol while taking Glioz 250mg Capsules is unknown. Kindly speak with your healthcare provider.

Storage:

Store at room temperature, away from moisture, heat, and light. Keep capsules in the original container and tightly closed.

How to use this Medication?

Take temozolomide capsules once daily at bedtime on an empty stomach with water, around the same time each day. Follow your doctor's instructions on treatment cycles, as the dosage schedule varies based on your type of brain tumor and response to treatment.

There may be multiple capsule types and colors in your entire dosage, as well as multiple prescription bottles. Pay close attention to the instructions on your prescription label, and ask your pharmacist or doctor to clarify any parts you don't understand.

Disclaimer:

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