Doxotero 50mg Injection contains Doxorubicin, an anthracycline-type chemotherapy drug commonly used to treat various cancers such as breast cancer, leukemia, lymphomas, and more.

Brand Name: Doxotero

Composition: Doxorubicin

Mechanism of Action:

By intercalating DNA strands, doxorubicin prevents cancer cells from replicating their DNA and synthesizing proteins. Additionally, it produces free radicals, which aid in cell death.

Uses:

• Breast cancer
• Ovarian cancer
• Hodgkin's and non-Hodgkin's lymphoma
• Leukemia
• Sarcoma

Dosage and Administration:

Intravenous (IV) infusion is the method of administration. The patient's body surface area and the kind of cancer being treated are taken into consideration while determining the dosage.

Side Effects:

• Nausea
• Vomiting
• Hair loss
• Diarrhea
• Weight gain
• Injection site reactions
• Fatigue
• Skin rash
• Mouth sores
• Low blood cell counts.

Safety Advise:

Liver  

Dosage modifications may be necessary for patients with hepatic impairment. Testing liver function should be done on a regular basis. Kindly speak with your healthcare provider.

Kidney  

Dosage modifications may be necessary for patients with renal impairment. Testing kidney function should be done on a regular basis. Kindly speak with your healthcare provider.

Pregnancy  

Due of its severe toxicity, doxorubicin should only be used if absolutely required during pregnancy. It may harm the fetus. Kindly speak with your healthcare provider.

Breast Feeding  

Because of the possibility of severe side effects in the infant, it is not recommended for nursing moms. Kindly speak with your healthcare provider.

Alcohol  

The safety of drinking alcohol while taking Doxotero 50mg Injection is uncertain. Kindly speak with your healthcare provider.

Storage:

Store the vials at 2°C to 8°C (36°F to 46°F) in a refrigerator. Do not freeze the solution.

How to use this Medication?

This medication is administered intravenously. A medical expert with specialized training administers it in a hospital or clinic. Inform your healthcare provider right away if you experience any odd feelings, such as pain, swelling, or burning, near the injection site.

Consult your pediatrician about this medication's use in kids. Extra caution could be required.

References:

1.    Carvalho C, Santos RX, Cardoso S, Correia S, Oliveira PJ, Santos MS, Moreira PI. Doxorubicin: the good, the bad and the ugly effect. Current medicinal chemistry. 2009 Sep 1;16(25):3267-85.

2.      Johnson-Arbor K, Dubey R. Doxorubicin.

3.      Rivankar S. An overview of doxorubicin formulations in cancer therapy. Journal of cancer research and therapeutics. 2014 Oct 1;10(4):853-8.

4.      Speth PA, Van Hoesel QG, Haanen C. Clinical pharmacokinetics of doxorubicin. Clinical pharmacokinetics. 1988 Jul;15:15-31.

5.      Patel AG, Kaufmann SH. How does doxorubicin work?. Elife. 2012 Dec 18;1:e00387.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Hetero Healthcare Limited

Address: S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.

Country of origin: India