Pemmet 100mg Injection contains Pemetrexed. This broad-spectrum antibiotic is used to treat serious bacterial infections, such as skin infections, urinary tract infections, meningitis, pneumonia, and intra-abdominal infections. It kills bacteria by preventing the formation of their cell walls.
Inform your doctor if you have heart, liver, or kidney issues or are taking other medications, as interactions may occur. Effective contraception is advocated for both men and women, and this medication is not advised during pregnancy or lactation.
Pemmet 100mg Injection contains Pemetrexed. This broad-spectrum antibiotic is used to treat serious bacterial infections, such as skin infections, urinary tract infections, meningitis, pneumonia, and intra-abdominal infections. It kills bacteria by preventing the formation of their cell walls.
Brand Name: Pemmet
Composition: Pemetrexed
Mechanism of Action:
Pemetrexed is an antifolate chemotherapeutic medication that functions by blocking important enzymes such as GAR Transformylase, Dihydrofolate Reductase, and Thymidylate Synthase that are involved in DNA synthesis and folate metabolism. It interferes with the synthesis of vital elements needed for the proliferation of cancer cells by preventing the synthesis of purines and pyrimidines. Rapidly dividing cancer cells are prevented from replicating by this inhibition, which ultimately results in cell cycle arrest and cell death.
Uses:
· Non-Small Cell Lung Cancer
· Malignant Pleural Mesothelioma
Dosage and Administration:
Pemmet 100mg Injection is administered intravenously under the supervision of an authorized medical professional. The kind, stage, and unique characteristics of each patient determine the dosage and treatment plan.
Side Effects:
· Nausea
· Vomiting
· Loss of appetite
· Fatigue
· Anemia
· Neutropenia
· Cough
· Diarrhea
Safety Advise:
Lungs
The safety of Pemmet Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Pemmet Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Pemmet Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Pemmet should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Using Pemmet while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Storage:
Keep out of direct sunlight and dampness, and store below 25°C. Avoid freezing.
References:
1. Chattopadhyay S, Moran RG, Goldman ID. Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications. Molecular cancer therapeutics. 2007 Feb 1;6(2):404-17.
2. Adjei AA. Pharmacology and mechanism of action of pemetrexed. Clinical lung cancer. 2004 Apr 1;5:S51-5.
3. Hazarika M, White RM, Johnson JR, Pazdur R. FDA drug approval summaries: pemetrexed (Alimta®). The oncologist. 2004 Sep 1;9(5):482-8.
4. Adjei AA. Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent. Clinical Cancer Research. 2004 Jun 15;10(12):4276s-80s.
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Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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