Tenolam E Tablet contains Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate is an antiretroviral medication used in the treatment of HIV-1 infection. 

Brand Name: Tenolam

Composition: Efavirenz, Tenofovir Disoproxil Fumarate, Lamivudine

Mechanism of Action:

Nucleoside reverse transcriptase inhibitors (NRTIs), such as tenofovir disoproxil fumarate and lamivudine, stop HIV from multiplying by blocking the reverse transcriptase enzyme, which is necessary for viral replication. HIV replication is further inhibited by efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI), which binds directly to the reverse transcriptase enzyme and changes its conformation to interrupt its action. These medications work together to lower the viral load and inhibit the spread of HIV infection.

Uses:

HIV-1 Infection

Dosage and Administration:

One tablet taken once a day, with or without food, is the usual dosage.

Side Effects:

• Fatigue
• Headache
• Nausea
• Vomiting
• Fever
• Cough
• Insomnia
• Liver Function Abnormalities
• Allergic Reactions

Safety Advise:

Kidney  

Monitor kidney function regularly, as Tenolam-E can cause nephrotoxicity. Kindly speak with your healthcare provider.

Liver  

Monitor liver function regularly, as Tenolam-E can cause liver impairement. Kindly speak with your healthcare provider.

Pregnancy  

Tenolam-E should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Tenolam-E while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Alcohol  

Tenolam-E should not be taken with alcohol. Kindly speak with your healthcare provider.

Storage:

Store Tenolam-E Tablet at a temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in the original packaging to protect them from light and moisture. Keep out of reach of children.

How to use this Medication?

Drink a glass of water along with this prescription. Take it daily at the same time as specified on the prescription label. Consume it with food. Take each dose exactly as directed on the prescription label for the best potential outcome from your therapy. Don't miss any dosages. The virus may become resistant to this and other medications if doses are skipped. Unless instructed otherwise by your care team, continue taking this therapy.

 
Discuss the usage of this drug in children with your care team. For certain illnesses, it can be administered to youngsters as young as 12, although there are safety precautions to take.

References:

1.   Pozniak AL, Gallant JE, DeJesus E, Arribas JR, Gazzard B, Campo RE, Chen SS, McColl D, Enejosa J, Toole JJ, Cheng AK. Tenofovir disoproxil fumarate,   emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes-a 96-week analysis. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2006 Dec 15;43(5):535-40.

2.      Frampton JE, Croom KF. Efavirenz/emtricitabine/tenofovir disoproxil fumarate: triple combination tablet. Drugs. 2006 Aug;66:1501-12.

3.      Dando TM, Wagstaff AJ. Emtricitabine/tenofovir disoproxil fumarate. Drugs. 2004 Sep;64:2075-82.

Disclaimer:

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Marketer details

Name: Hetero Drugs Ltd

Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA

Country of origin: India