Phesgo 600mg/600mg Solution for Injection is a combination medicine that contains Pertuzumab and Trastuzumab. Breast cancer that is HER2-positive is treated with it. The HER2 receptor, a protein that stimulates the proliferation of cancer cells, is the target of the combination.
Inform your healthcare team about all medications, avoid during pregnancy or breastfeeding, and use effective contraception during treatment.
Phesgo 600mg/600mg Solution for Injection is a combination medicine that contains Pertuzumab and Trastuzumab. Breast cancer that is HER2-positive is treated with it. The HER2 receptor, a protein that stimulates the proliferation of cancer cells, is the target of the combination.
Brand Name: Phesgo
Composition: Pertuzumab, Trastuzumab
Mechanism of Action:
The HER2 receptor, a protein that is overexpressed in some breast tumors, is the target of pertuzumab. It prevents HER2 from dimerizing with other HER receptors by binding to a different epitope on the HER2 receptor than trastuzumab. The anticancer activity is enhanced by this dual blockage. Whereas trastuzumab is a monoclonal antibody that attaches itself to the HER2 receptor's extracellular domain (Subdomain IV), causing it to be downregulated and destroyed.
Uses:
Breast Cancer
Dosage and Administration:
Compared to separate intravenous infusions of pertuzumab and trastuzumab, Phesgo is easier to administer and is supplied as a subcutaneous injection. Typically, the initial injection takes around eight minutes, then the subsequent injections take roughly five minutes.
Side Effects:
Safety Advise:
Lungs
The safety of Phesgo for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Phesgo for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Phesgo for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Phesgo should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Using Phesgo while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Storage:
Store in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze.
Disclaimer:
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Marketer details
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Country of origin: India
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