Klacid IV Injection

Klacid IV Injection contains Clarithromycin, a type of macrolide antibiotic used to treat serious bacterial infections. In hospital settings, it is given intravenously to treat diseases such skin infections, bronchitis, and pneumonia.

Brand Name: Klacid

Composition: Clarithromycin

Mechanism of Action:

Clarithromycin suppresses protein synthesis by attaching itself to the 50S subunit of bacterial ribosomes and preventing aminoacyl-tRNA from translocating during translation. By doing this, bacteria are unable to produce vital proteins that are necessary for their development and reproduction. Because of this, clarithromycin mainly functions as a bacteriostatic agent, preventing the growth of bacteria, while it can also have bactericidal effects at higher dosages or against species that are extremely vulnerable. It has little effect on human ribosomes and is only effective against bacterial cells.

Uses:

·        Community-acquired pneumonia

·        Acute bacterial exacerbation of chronic bronchitis (AECB)

·        Acute maxillary sinusitis

·        Skin and soft tissue infections

Dosage and Administration:

Adults should take 500 mg of Klacid IV slowly over the course of 60 minutes every 12 hours.

Side Effects:

·       Nausea

·       Vomiting

·       Abdominal pain

·       Diarrhea

Safety Advise:

Lungs  

The safety of Klacid IV for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Klacid IV for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Klacid IV for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Klacid IV should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Klacid IV while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Use the reconstituted solution within 24 hours if it is refrigerated, and keep Klacid IV vials below 25°C and out of direct sunlight.

References:

1.     Medicines.org.uk. 2020. [online]

2.     Drugs, H., 2020. Clarithromycin: Medlineplus Drug Information. [online] Medlineplus.gov.

3.     Mri.cts-mrp.eu. 2020. [online]

4.     Pubchem.ncbi.nlm.nih.gov. 2020. Clarithromycin. [online]

Disclaimer:

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