Progynova 2mg Tablet is a prescription drug that contains Estradiol valerate, a kind of estrogen. It is generally used in hormone replacement therapy (HRT) to control symptoms associated with estrogen shortage, especially in postmenopausal women.

Brand Name: Progynova

Composition: Estradiol Valerate

Mechanism of Action:

Estradiol valerate is metabolized by the body into estradiol, a natural estrogen. It binds to estrogen receptors in various organs, including the uterus, breast, bone, and brain. This hormone-receptor complex modulates gene expression and reinstates estrogen action. It alleviates menopausal symptoms and protects bone loss due to estrogen shortage.

Uses:

·       Menopausal Symptom Relief

·       Osteoporosis Prevention

·       Estrogen Deficiency Treatment

Dosage and Administration:

1 tablet (2 mg) is used orally once per day, ideally after a meal. Typically consists of a 21-day program followed by a 7-day respite. Your doctor may change the dosage based on your specific needs.

Side Effects:

·       Headache​

·       Breast tenderness​

·       Abdominal pain​

·       Vaginal discharge​

·       Mood changes​

·       Weight gain​

·       Nausea​

·       Swelling of legs

·       Changes in libido

Safety Advise:

Lungs  

The safety of Progynova for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Progynova for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Progynova for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Progynova should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Progynova while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Keep below 77°F (25°C). Keep out of direct sunlight and moisture. The tablets should not be refrigerated. Keep out of children's and pets' reach.

How to use this Medication?

Take this medication orally. Observe the medicine label's instructions. It can be taken with or without meals. Take it with meals if it makes you feel nauseous. As instructed on the label, take this medication at the same time every day. Never take your medication more frequently than is recommended.

Every prescription and refill will come with a patient package insert for the medicine. Every time, thoroughly read this material. The sheet might be updated often.

References:

1.     Brawer JR, Munoz M, Farookhi R. Development of the polycystic ovarian condition (PCO) in the estradiol valerate-treated rat. Biology of reproduction. 1986 Oct 1;35(3):647-55.

2.     Wellington K, Perry CM. Estradiol valerate/dienogest. Drugs. 2002 Feb;62:491-504.

3.     Jensen JT. Evaluation of a new estradiol oral contraceptive: estradiol valerate and dienogest. Expert opinion on pharmacotherapy. 2010 May 1;11(7):1147-57.

4.     Quirarte GL, Reid LD, de la Teja IS, Reid ML, Sánchez MA, Díaz-Trujillo A, Aguilar-Vazquez A, Prado-Alcalá RA. Estradiol valerate and alcohol intake: dose-response assessments. BMC pharmacology. 2007 Dec;7:1-4.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Bayer Zydus Pharma Pvt Ltd

Address: Bayer House, Central Avenue, Hiranandani Estate, Thane (west) Thane 400607 India

Country of origin: India