Kabonib 20mg Tablet contains Cabozantinib, an oral medication used primarily for the treatment of certain types of cancer, including medullary thyroid cancer and renal cell carcinoma. Targeting multiple receptor tyrosine kinases implicated in tumor development, angiogenesis, and metastasis, cabotinib is a multi-tyrosine kinase inhibitor.

Brand Name: Kabonib

Composition: Cabozantinib

Mechanism of Action:

Numerous tyrosine kinases, including as MET, VEGFR, and AXL, which are essential for the growth, survival, and blood vessel development of cancer cells, are inhibited by cabotinib. Cabozantinib aids in reducing the growth and spread of tumors by blocking these mechanisms.

Uses:

• Medullary Thyroid Cancer
• Renal Cell Carcinoma

Dosage and Administration:

For renal cell carcinoma and medullary thyroid cancer, the usual initial dosage is 60 mg once daily and 140 mg once daily, respectively. Depending on the patient's condition and reaction to treatment, the precise dosage may change. Cabozantinib should be taken orally, with or without food, at the same time every day. It is best to swallow tablets whole rather than chewing or crushing them.

Side Effects:

·         Rash

·         Hypertension

·         Diarrhea

·         Fatigue

·         Nausea

·         Vomiting

·         Shortness of breath

·         Bone pain

·         Hand foot syndrome

·         Loss of appetite

·         Dry skin

·         Cough

Safety Advise:

Liver  

Cabozantinib can harm the liver and raise liver enzymes. Regular liver function tests are recommended, particularly for people who already have liver disease. Kindly speak with your healthcare provider.

Kidney  

Regular kidney function tests are recommended, particularly for people who already have renal disease. Kindly speak with your healthcare provider.

Pregnancy  

Cabozantinib may be harmful to the developing fetus. During treatment, effective contraception should be used. Kindly speak with your healthcare provider.

Breast Feeding  

It is not known if Cabozantinib is excreted in breast milk; therefore, breastfeeding is generally not recommended during treatment. Kindly speak with your healthcare provider.

Alcohol  

The safety of combining Kabonib 20mg Tablet with alcohol is unknown. Kindly speak with your healthcare provider.

Storage:

Store at room temperature (15°C to 30°C) in a dry place, away from light and moisture.

How to use this Medication?

This medication should be taken orally with water. Take it daily at the same time as specified on the prescription label. This medication should not be chewed, crushed, or sliced. Completely swallow the pills or capsules. At least one hour before and two hours after eating, take it without food. Unless instructed otherwise by your healthcare provider, continue taking it.

Consult your physician regarding this medication's use in children. Precautions are necessary even though it may be given for some conditions in youngsters as young as twelve.

Disclaimer:

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