Gemibine 1.4gm Injection contains Gemcitabine, an anticancer drug. Its primary use is in the treatment for multiple cancers.

Brand Name: Gemibine

Composition: Gemcitabine

Mechanism of Action:

Gemcitabine is a pyrimidine nucleoside analog, a form of antimetabolite. It becomes integrated into the DNA of quickly proliferating cells (like cancer cells), obstructing the synthesis of new DNA and halting the division of existing cells. This eventually leads to cell death, particularly in cancer cells that divide more quickly than normal cells.

Uses:

• Non-Small Cell Lung Cancer
• Pancreatic Cancer
• Bladder Cancer
• Breast Cancer
• Ovarian Cancer

Dosage and Administration:

It is given intravenously, or into a vein, under a medical professional's supervision. The dosage and duration depend on factors such as the type of cancer, body surface area, and the patient's response to the treatment.

Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Loss of appetite
• Anemia
• Neutropenia
• Thrombocytopenia
• Fever
• Fatigue
• Flu-like symptoms
• Weight loss
• Rash
• Jaundice
• Swelling
• Shortness of breath

Safety Advise:

Kidney  

Renal patients need to be closely watched because there is a possibility of toxicity. Kindly speak with your healthcare provider.

Liver  

Liver patients need to be closely watched because there is a possibility of toxicity. Kindly speak with your healthcare provider.

Pregnancy  

Administering Gemibine 1.4gm injection while pregnant is dangerous because there is clear evidence that they cause a risk to the growing fetus. Kindly speak with your healthcare provider.

Breast Feeding  

Gemibine 1.4gm Using an injection while nursing is dangerous. Evidence points to the possibility of medication poisoning in a growing baby. Kindly speak with your healthcare provider.

Alcohol  

It is not advised to use alcohol while under this medication since Gemibine 1.4gm may cause drowsiness and tiredness. Kindly speak with your healthcare provider.

Driving  

Your driving abilities may be affected by a Gemibine 1.4gm injection. When using this medication, don't drive. Kindly speak with your healthcare provider.

Storage:

Store in a refrigerator at 2°C to 8°C. Do not freeze.

How to use this Medication?

This medication is infused into a vein. It is given at a hospital or clinic by a medical expert with specialized training.

Consult your pediatrician about the usage of this medication in young patients. There might be a need for extra caution.

Overdosage: Contact an emergency department or poison control center right away if you believe you may have taken too much of this medication.

References:

1.      Hui YF, Reitz J. Gemcitabine: a cytidine analogue active against solid tumors. American journal of health-system pharmacy. 1997 Jan 15;54(2):162-70.

2.      Aapro MS, Martin C, Hatty S. Gemcitabine—a safety review. Anti-cancer drugs. 1998 Mar 1;9(3):191-202.

3.      Toschi L, Finocchiaro G, Bartolini S, Gioia V, Cappuzzo F. Role of gemcitabine in cancer therapy. Future oncology. 2005 Feb 28;1(1):7-17.

4.      Barton-Burke M. Gemcitabine: a pharmacologic and clinical overview. Cancer nursing. 1999 Apr 1;22(2):176-83.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India