Jakavi Tablet contains Ruxolitinib. It is an inhibitor of Janus kinase (JAK) that is mainly used to treat cancer and several blood problems.
If you take other medications or have liver or renal problems, let your doctor know since there may be interactions. Avoid using it when pregnant or nursing; throughout therapy, good contraception is crucial.
Jakavi Tablet contains Ruxolitinib. It is an inhibitor of Janus kinase (JAK) that is mainly used to treat cancer and several blood problems.
Brand Name: Jakavi
Composition: Ruxolitinib
Mechanism of Action:
JAK1 and JAK2 enzymes, which are involved in the signaling pathways for blood cell formation and inflammatory reactions, are inhibited by rufolitinib. By doing this, it lessens symptoms like spleen enlargement and systemic inflammation and helps regulate aberrant blood cell synthesis.
Uses:
Dosage and Administration:
It is advised to take Jakavi with or without food. The tablet should not be split, chewed, or crushed. Skip the missed dose and take the subsequent one at the scheduled time. Avoid taking two doses at once.
Side Effects:
Safety Advise:
Lungs 
The safety of Jakavi for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Jakavi for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Jakavi for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Jakavi should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Using Jakavi while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Storage:
Maintain storage between 15°C and 30°C (59°F and 86°F). Keep away from moisture and in a dry location. Store away from moist areas like bathrooms.
How to use this Medication?
Ruxolitinib is available as an oral tablet. It is often taken twice a day, either with or without food. Take ruxolitinib daily at around the same times. Pay close attention to the instructions on your prescription label, and ask your pharmacist or doctor to clarify any parts you don't understand. Ruxolitinib should be taken precisely as prescribed. Never take more or less of it, or take it more frequently than your doctor has suggested.
Ruxolitinib is begun at a low dose for PV or myelofibrosis and increased progressively every two weeks. Dosing for GVHD is modified according to response, and for chronic patients, weaning is done gradually after six months.
Disclaimer:
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Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: Switzerland
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