Mozifor 24mg Injection contains Plerixafor, a hematopoietic stem cell mobilizer. In patients with specific malignancies, it is used to increase the release of bone marrow stem cells into the bloodstream for collection and transplantation.

Brand Name: Mozifor

Composition: Plerixafor

Mechanism of Action:

A CXCR4 receptor antagonist called plerixafor interferes with the way that bone marrow stem cells' CXCR4 receptor and stromal cell-derived factor-1α (SDF-1α) interact. Hematopoietic stem cells are released into the peripheral circulation by inhibiting this connection, allowing for their collection for use in stem cell transplantation. By increasing the availability of stem cells, this process makes it easier to harvest them and increases the success rate of transplantation treatments.

Uses:

Stem Cell Transplant

Dosage and Administration:

Subcutaneous (SC) administration of 0.24 mg/kg between 6 and 11 hours before apheresis.

Side Effects:

·       Nausea

·       Vomiting

·       Diarrhea

·       Fatigue

·       Headach

·       Dizziness.

·       Injection site reactions (redness, pain, swelling)

Safety Advise:

Lungs  

The safety of Mozifor Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Mozifor Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Mozifor Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

  Pregnancy  

Mozifor should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Mozifor while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Mozifor should be kept in the refrigerator between 2°C and 8°C (36°F and 46°F). The formulation may be harmed by freezing, so avoid doing so.

How to use this Medication?

Plerixafor injection is a liquid that a physician or nurse administers subcutaneously, or beneath the skin, in a medical facility. For up to four consecutive days, it is typically administered once daily, eleven hours before to the blood cell extraction. You will start receiving a G-CSF medicine once daily for four days before to starting plerixafor injection treatment, and you will continue to get the G-CSF medication during your plerixafor injection treatment.

Disclaimer:

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