Fragmin 5000IU Injection contains Dalteparin sodium, a low molecular weight heparin. Its main purpose is to prevent and cure dangerous blood clots, including pulmonary embolism, deep vein thrombosis, and acute coronary syndrome consequences. It is also used to stop clots from forming in people who are having surgery or who have acute illnesses that limit their mobility.

Brand Name: Fragmin

Composition: Dalteparin sodium

Mechanism of Action:

Antithrombin III, a naturally occurring clotting factor inhibitor, is activated by daltoneparin sodium. It mostly inhibits Factor Xa, with thrombin (Factor IIa) being inhibited to a lesser degree. By stopping prothrombin from becoming thrombin and fibrinogen from becoming fibrin, this inhibition lowers the risk of clot formation. Compared to unfractionated heparin, it provides more consistent anticoagulant effects since it is a low molecular weight heparin (LMWH).

Uses:

Prevention of Blood Clots

Dosage and Administration:

Dosage of administration is subcutaneous injection, usually given by a medical practitioner. The condition being treated, the patient's weight, and other variables may affect the dosage.

Side Effects:

·       Bleeding

·       Injection site reactions, such as pain, redness, or swelling

·       Bruising

·       Decreased platelet count

·       Difficulty breathing

·       Swelling of the face and throat

·       Osteoporosis

·       Hair loss

Safety Advise:

Lungs  

The safety of Fragmin Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Fragmin Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Fragmin Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Fragmin should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Fragmin while nursing is most likely dangerous. Kindly speak with your healthcare provider

Storage:

Do not freeze; inject between 2°C and 8°C (refrigerated), shielded from light.

How to use this Medication?

Depending on age and condition, dalteparin is usually administered as a subcutaneous injection once or twice a day. It is taken for 5–8 days for angina or heart attacks, and for 5–10 days beginning on the day of surgery following surgery. It is administered for 12–14 days to patients on bed rest in order to prevent DVT. Treatment for DVT caused by cancer may last up to six months.

References:

1.      Hull RD, Pineo GF. Dalteparin sodium. Expert Opinion on Pharmacotherapy. 2001 Aug 1;2(8):1325-37.

2.      Pineo GF, Hull RD. Dalteparin sodium. Expert Opinion on Pharmacotherapy. 2001 Aug 1;2(8):1325-37.

3.      Botezatu C. Dalteparin sodium. Reactions. 1841 Feb;90(6):2021.

4.      Waheed F. Dalteparin sodium/enoxaparin sodium/heparin. Reactions. 2003 Dec 6;980:6.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Pfizer Ltd

Address: The Capital, 1802, 18th Floor, Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Country of origin: Belgium